Silybin/Silymarin treatment in chronic hepatitis C.
نویسندگان
چکیده
منابع مشابه
Differences in the disposition of silymarin between patients with nonalcoholic fatty liver disease and chronic hepatitis C.
Silymarin, derived from the milk thistle plant Silybum marianum and widely used for self-treatment of liver diseases, is composed of six major flavonolignans including silybin A and silybin B, which are the predominant flavonolignans quantified in human plasma. The single- and multiple-dose pharmacokinetics of silymarin flavonolignans were examined in patients with nonalcoholic fatty liver dise...
متن کاملSilymarin/Silybin and Chronic Liver Disease: A Marriage of Many Years.
Silymarin is the extract of Silybum marianum, or milk thistle, and its major active compound is silybin, which has a remarkable biological effect. It is used in different liver disorders, particularly chronic liver diseases, cirrhosis and hepatocellular carcinoma, because of its antioxidant, anti-inflammatory and antifibrotic power. Indeed, the anti-oxidant and anti-inflammatory effect of silym...
متن کاملMilk thistle in liver diseases: past, present, future.
Silybum marianum or milk thistle (MT) is the most well-researched plant in the treatment of liver disease. The active complex of MT is a lipophilic extract from the seeds of the plant and is composed of three isomer flavonolignans (silybin, silydianin, and silychristin) collectively known as silymarin. Silybin is a component with the greatest degree of biological activity and makes up 50% to 70...
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Background and purpose: Silymarin, a standardized extract of the milk thistle seeds, has been widely used to treat chronic hepatitis, cirrhosis, and other types of toxic liver damage. Despite increasing studies on the action of silymarin and its major active constituent, silybin in their therapeutic properties against insulin resistance, diabetes and hyperlipidaemia in vitro and in vivo, the me...
متن کاملA Review on Hepatoprotective Activity of Silymarin
Silymarin is obtained from the seeds of Silybum marianum (milk thistle), an edible plant that has been used medicinally from ancient times for the treatment of various liver disorders. It is widely prescribed by herbalists and has almost no known side effects. The plant is native to the Mediterranean and grows throughout Europe, North America, India, China, South America, Africa and Australia. ...
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ورودعنوان ژورنال:
- Annals of hepatology
دوره 11 5 شماره
صفحات -
تاریخ انتشار 2012